RG Pharmaceutica-
Clopidogrel - antiplatelet agent. Effect of the drug
carried by the ability of clopidogrel to inhibit the binding
of selective adenosine receptor platelet activation is inhibited whereby the
complex of the glycoproteins IIb / IIIa and reduced platelet aggregation. The
drug increases the bleeding time.
After oral administration, the drug is rapidly absorbed from the gastrointestinal tract. Bioavailability is about 50% and is independent of food intake. Clopidogrel - a prodrug, is metabolized in the liver to form the active substance - thiol metabolite of clopidogrel. The major metabolite is a carboxylic acid derivative, which determine the pharmacokinetic profile. The peak plasma concentration of drug observed 60 minutes after oral administration. Return with urine and feces as metabolites. The half-life of about 8 hours.
Mian Khalid Mehmood RG Pharmaceutica can produce these purified medicines.
Mian Khalid Mehmood RG Pharmaceutica
product Clopidogrel
antiplatelet effect is dose-dependent, with the use of the drug at the
recommended therapeutic doses, the maximum therapeutic effect develops within
3-7 days. Preparation irreversibly blocking platelet ADP-receptor, so that
they lose the ability to aggregate, the restoration of normal function observed
7 days after discontinuation of the drug, as updates platelets.After oral administration, the drug is rapidly absorbed from the gastrointestinal tract. Bioavailability is about 50% and is independent of food intake. Clopidogrel - a prodrug, is metabolized in the liver to form the active substance - thiol metabolite of clopidogrel. The major metabolite is a carboxylic acid derivative, which determine the pharmacokinetic profile. The peak plasma concentration of drug observed 60 minutes after oral administration. Return with urine and feces as metabolites. The half-life of about 8 hours.
Mian Khalid Mehmood RG Pharmaceutica can produce these purified medicines.
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